Curcumin Amathandizira Kuyiwala

Kudya pafupipafupi kwa curcumin kumalimbitsa kukumbukira komanso kumanenedwa kuti kumathandiza ndi matenda a Alzheimer's. Chomera chotsutsana ndi kutupa ndi antioxidant chomwe chimapezeka mu turmeric chiyenera kukhala gawo la zakudya kawiri pa tsiku.

Curcumin - Pawiri yomwe imapezeka mu turmeric imathandizira kuiwala

Curcumin imadziwika kuti anti-inflammatory and antioxidant plant substance. Anthu akhala akukayikira kuti kumwa turmeric pafupipafupi komanso pafupipafupi kungakhale chifukwa chomwe anthu okalamba ku India sangakhale ndi matenda a Alzheimer's, salimbana ndi kuiwala kaŵirikaŵiri, ndipo nthawi zambiri amakhala ndi maganizo abwino kusiyana ndi anthu a msinkhu womwewo m'mayiko otukuka akumadzulo.

Zotsatira za ubongo

Pepala lasayansi lochokera ku 2008 lidafotokozera kale mwatsatanetsatane momwe turmeric kapena curcumin ingathane ndi kusintha kwaubongo komwe kumafanana ndi Alzheimer's:

• Mu Alzheimer's muli u. njira zotupa mu ubongo zimagwira ntchito - ndipo curcumin (ikhoza kudutsa mu ubongo) imakhala ndi anti-inflammatory effect.
• Mu Alzheimer's pali kupsinjika kwakukulu kwa okosijeni mu ubongo - ndipo curcumin imakhala ndi antioxidant effect.
• Madipoziti azitsulo muubongo amatha kuwonedwa mu Alzheimer's - ndipo curcumin ndi gawo lofunikira pamapulogalamu ochotsa poizoni chifukwa chazomwe zimamangiriza zitsulo.
• Ndi Alzheimer's, pali madipoziti mu ubongo - ndipo curcumin imatsimikizira kuti macrophages (maselo a scavenger) akhoza kusweka ndi kusungunula madipozitiwa bwino.
• Alzheimer's imayambitsa kuwonongeka kwa myelin sheath, wosanjikiza womwe umateteza ma cell a mitsempha muubongo. Curcumin imatha kulimbikitsa kusinthika kwa gawo lotetezali.

Tidapereka chidule chatsatanetsatane chazinthu zonsezi za curcumin m'nkhani yathu ya turmeric ndi Alzheimer's. Nthawi zambiri, komabe, maphunziro oyambira ndi kufufuza panthawiyo anali zitsanzo za Alzheimer's, mwachitsanzo, osati maphunziro azachipatala pa anthu.

Kafukufuku wachipatala pa zotsatira za curcumin pakuyiwala

Asayansi aku University of California adafalitsa kafukufuku wokhudza anthu mu Januware 2018 mu American Journal of Geriatric Psychiatry. Anafufuza ngati supplementation ndi curcumin ingathandize kukumbukira anthu omwe ali ndi kuiwala kwa zaka. Kuphatikiza apo, chikoka cha curcumin pama depositi wamba a Alzheimer's muubongo adawunikidwa mwa odwala a Alzheimer's.

"Zomwe curcumin imagwirira ntchito muubongo sizimamveka bwino. Timakhulupirira kuti curcumin ikhoza kuchepetsa njira mu ubongo zomwe zimagwirizanitsidwa ndi Alzheimer's ndi kuvutika maganizo, "anatero Dr. Gary Small, wolemba kafukufuku komanso wamkulu wa geriatric psychiatry ku yunivesite ya California.
Phunziro loyang'aniridwa kawiri, loyang'aniridwa ndi placebo linachitidwa kwa akuluakulu a 40 pakati pa zaka za 50 ndi 90. Onse anali atavutika kale ndi zizindikiro zoyamba za kuiwala ndipo tsopano alandira 90 mg micellar curcumin kawiri tsiku lililonse kapena kukonzekera kwa placebo kwa 18. miyezi.

Kulekerera kunali kwabwino kwambiri. Maphunziro anayi okha a curcumin adanenanso ululu wa m'mimba, komanso awiri ochokera ku gulu la placebo.

Kusintha kwakukulu pakukumbukira bwino

Phunziroli lisanayambe komanso miyezi isanu ndi umodzi iliyonse pambuyo pake, chidziwitso cha ogwira nawo ntchito chinayesedwa. Kumayambiriro ndi kumapeto, chiwerengero cha madipoziti mu ubongo wa anthu (amyloid plaques ndi tau proteins) adafufuzidwanso pogwiritsa ntchito PET scan (positron emission tomography).

Gulu la curcumin tsopano linawonetsa kusintha kwakukulu mu kukumbukira ndi kusinkhasinkha. Palibe chomwe chidachitika m'gulu la placebo. Poyesa kukumbukira, gulu la curcumin lidatha kupititsa patsogolo ntchito yawo ndi 28 peresenti mkati mwa miyezi 18. Komanso maganizo ake anasintha.

Zosungira mu ubongo zimachepa

Zinalinso zosangalatsa kwambiri kuti PET scan inawonetsa kuwonongeka koonekera kwa ma depositi muubongo. Makamaka mu amygdala ndi hypothalamus, curcumin yachepetsa plaque ndi mapuloteni a tau. M'gulu la placebo, kumbali ina, zonse zinali zofanana pankhaniyi.

The amygdala ndi hypothalamus ndi malo aubongo komwe kumagwira ntchito zingapo zamakumbukiro komanso luso lamalingaliro. Kusokonekera kwa amygdala kumatha kuwonekera muzovuta za kukumbukira, kukhumudwa, ndi mantha. Komanso nthawi zambiri sizingatheke kuunika momwe zinthu zilili m'maganizo ngati pali kuwonongeka m'derali.

Curcumin motsutsana ndi kuiwala

"Zotsatira zathu zimasonyeza kuti kutenga curcumin kwa zaka kungapereke phindu lalikulu lachidziwitso," akumaliza Dr. Small.
Chifukwa chake ngati mukufuna kuchitapo kanthu panthawi yake motsutsana ndi kuyiwala komwe kumachitika nthawi zambiri muukalamba kapena kupewa, turmeric iyenera kukhala zokometsera zokhazikika kukhitchini.

Mupeza maphikidwe 50 okhala ndi ufa wa turmeric ndi mizu yamasamba atsopano pamasamba opitilira 100. Kuphatikiza apo, bukhuli lili ndi machiritso a 7-day turmeric, momwe mungaphunzire kugwiritsa ntchito turmeric mumtengo wokoma koma wofunikira pafupifupi pafupifupi mbale iliyonse - kaya kadzutsa, chamasana, supu yamadzulo, kugwedeza, kapena smoothie.

Ngati mukufunanso kugwiritsa ntchito curcumin zakudya zowonjezera, chonde dziwani kuti curcumin imatengedwa bwino kangapo patsiku kuti mukwaniritse mlingo wokhazikika wa curcumin m'magazi. Mu phunziro lomwe lili pamwambapa, 90 mg micellar curcumin idagwiritsidwa ntchito kawiri pa tsiku. Micellar curcumin imanenedwa kuti ili ndi bioavailability yapamwamba kuposa "yachibadwa" curcumin kotero kuti mlingo wochepa wotchulidwa ndi wokwanira. (Ndi curcumin wamba mumatenga 2000 mg wa curcumin tsiku lililonse).