Danielle Moore
Hiki iā ʻoe ke lawe i ka lāʻau K2 inā ʻoe e lawe i nā antagonist vitamin K e like me ka macular a me ka warfarin? ʻO nā lāʻau lapaʻau ʻelua i kapa ʻia ma ke ʻano he mea hoʻokahe koko. Kāohi lākou i ke koko koko a ʻōlelo ʻia e pale i ka hōʻeha puʻuwai a me ka hahau ʻana.
Hiki iā ʻoe ke lawe inā lawe ʻoe i nā mea hoʻokahe koko?
ʻO ka Vitamin K2 kahi huaʻai koʻikoʻi. No kekahi mau makahiki, ua hoʻonui ʻia ka lawe ʻana i ka lāʻau K2 ma ke ʻano he meaʻai meaʻai, ʻoi aku ka hui pū me ka huaora D. ʻOiai ʻo ka huaora D e hoʻoikaika i ka absorption o ka calcium mai ka ʻōpū, ua manaʻo ʻia ka huaora K2 e hōʻoia i ka hāʻawi hou ʻana o ka calcium, ʻo ia hoʻi. komo i loko o ka iwi a ʻaʻole e waiho ʻia ma nā paia o ke aʻa koko.
Eia nō naʻe, nui ka poʻe e lawe i ka lāʻau antagonist vitamin K - ʻike ʻia hoʻi ʻo nā mea hoʻokahe koko. I kēia manawa, ua ʻōlelo ʻia ua pāpā loa ʻia ka lawe ʻana i ka vitamina K2 i kēia hihia. No laila, paʻakikī pinepine ka poʻe i hoʻopilikia ʻia me nā hopena o ka hemahema o ka huaora K2. I kēia manawa, ke hoʻonui nei nā hōʻike ʻaʻole pono e lawe ʻia ka huaora K2 inā ʻoe e lawe i nā mea hoʻokahe koko akā pono e lawe ʻia e noho olakino a pale i nā hopena ʻaoʻao.
Akā, ke kōkua mau nei nā mea hoʻokahe koko? Ma hope o nā mea a pau, pili ko lākou hopena i ka pale ʻana i ka hopena vitamin K2, no laila ʻaʻole kūpono ka lawe ʻana i ka huaora K2 ma aneʻi.
(E hoʻomaopopo: ʻO kēia wale nō e pili ana i nā mea hoʻokahe koko o ka ʻano antagonist vitamin K (eg macular, warfarin, etc.). No laila ʻaʻole ia e pili ana i nā lāʻau hoʻokahe koko a i ʻole nā lāʻau anticoagulant e like me ASA, clopidogrel, rivaroxaban, etc.
Loaʻa i ka Vitamin K kēia mau hana i ke kino
Hoʻokomo ʻia ka Vitamin K i nā hana like ʻole i ke kino. No ka laʻana, mālama ia i ka mineralization maikaʻi o nā iwi, ʻo ia hoʻi ka iwi iwi kiʻekiʻe, a no laila ua manaʻo ʻia he mea pale koʻikoʻi e pili ana i ka osteoporosis. Eia kekahi, hoʻoponopono ka huaora K i ka pae calcium i loko o ke koko, i ka manawa like e pale ai i ka calcification o nā kīʻaha koko.
ʻO kekahi o nā hana nui o ka vitamina K ʻo ia hoʻi ka hoʻokumu ʻana i nā mea i kapa ʻia coagulation. ʻO kēia kekahi mau protein i loko o ke koko e hōʻoia i ka wā e hōʻeha ai ke koko a hoʻomaka ka ʻeha e hoʻōla.
Inā hoʻopau ʻia ka hana o kēia mau mea coagulation ma muli o kahi kīnā genetic, hiki iā ʻoe ke hoʻokahe i ke koko a make mai nā ʻeha liʻiliʻi loa (hemophilia).
ʻO kēia ke ʻano o ka hana ʻana o nā mea hoʻokaʻawale koko mai ka hui o nā antagonist vitamin K
ʻO nā mea hoʻoheheʻe koko mai ka hui o nā huaʻai K antagonists, no ka laʻana, warfarin (eg Coumadin) a me phenprocoumon (eg Marcumar a i ʻole Marcoumar) (18). Hoʻopili pololei kēia mau mea i ka pōʻai vitamin K. No ka mea, ke kaʻe nei lākou i kahi enzyme e hoʻāla maʻamau i ka huaora K i hana ʻole i ka wā e pono ai, ʻo ia hoʻi ke koi ʻia nā mea clotting hou.
No laila, emi ka pae o ka huaora K ikaika i loko o ke koko. ʻOi aku ka liʻiliʻi o nā mea coagulation i kēia manawa a ʻo ke koko ke ʻano "māmā". I ka manawa like, ʻaʻole nalo ka huaora K no nā hana koʻikoʻi ʻē aʻe (ka iwi iwi, pale i ka osteoporosis, pale i ka calcification o nā kīʻaha koko (= arteriosclerosis).
Hiki i nā mea hoʻokahe koko ke loaʻa kēia mau hopena a me nā hopena ʻaoʻao
Ma muli o ka hoʻokaʻawale ʻana o ke koko i ka vitamin K antagonists, ʻo ka hopena ʻaoʻao maʻamau o kēia mau lāʻau lapaʻau ʻo ke koko "ʻoi aku ka lahilahi," hiki ke alakaʻi i ke koko i loko. Ua hōʻike ʻia kahi haʻawina 2013 he 41 pakeneka o nā maʻi maʻi hahau 100 i loaʻa i ke koko o loko ma hope o ka lawe ʻana i nā antagonists vitamin K no ka awelika o 19 mau mahina.
Ua hōʻike ʻia kahi noiʻi mai 2016 ʻo nā lāʻau lapaʻau (i nā mea maʻi me ka fibrillation atrial e koi ana i ka dialysis) ʻaʻole i hoʻonui wale i ka hopena o ke koko akā ʻaʻole i hōʻike i ka hopena i ʻōlelo ʻia. ʻAʻole lākou i hōʻemi i ka pilikia o ka hahau ʻana a i ʻole ka make.
Ua hōʻike pū ʻia kahi noiʻi mai 2006 i nā poʻe maʻi i lawe mau i ka lāʻau antagonist K ua loaʻa i nā haʻihaʻi ma muli o ka hemahema o ka huaora K i loaʻa i kēia manawa ma mua o nā poʻe maʻi ʻaʻole pono e lawe i ia lāʻau lapaʻau. A ua hōʻike ʻia kahi noiʻi 2015 i nā poʻe maʻi kahiko (60 a 80 mau makahiki) i ka piʻi ʻana o ka osteoporosis a me ke atherosclerosis me ka hoʻohana lōʻihi o ka warfarin.
ʻElua mau noiʻi mai 2012 a me 2016 i ʻike pū ʻia ua hoʻonui nui ʻia nā antagonist vitamin K i ka hopena o ka arteriosclerosis.
No laila, ʻo ka mea e lawe ana i ka huaʻai K antagonists e loaʻa koke a ma hope paha i ka hemahema o ka huaora K a hiki ke loaʻa i nā hopena kūpono o kēia hemahema. No laila, pono anei ʻoe e lawe i ka huaʻa K inā ʻoe e lawe i nā mea hoʻokahe koko e pale ai i ka nele o ka vitamina K? A i ʻole ʻaʻole ʻoi aku ka maikaʻi o nā antagonist vitamin K?
ʻO kēia ke ʻano o ka hana ʻana o ka huaora K ke lawe ʻoe me nā mea kūʻē i ka huaora K
A hiki i kēia manawa, ua ʻōlelo ʻia nā poʻe maʻi e lawe ana i nā mea hoʻokaʻawale koko ʻano antagonist K ʻaʻole e ale i nā mea hoʻohui vitamin K a ʻoi aku ka maikaʻi o ka ʻai ʻole i nā meaʻai he nui i ka vitamina K, e like me ka spinach, Swiss chard, kale, broccoli, etc.
Akā ʻoiaʻiʻo, ua hōʻike ʻia i loko o kahi noiʻi mai 2007 hiki i ka liʻiliʻi loa o ka vitamina K ke pilikia i nā maʻi. Ua ʻike ʻia ʻo ka poʻe maʻi e lawe ana i ka warfarin akā e ʻeha mau ana i ka piʻi ʻana o nā pae INR i ʻai ʻia i ka meaʻai ʻoi aku ka liʻiliʻi o ka huaora K ma mua o nā maʻi i paʻa nā pae INR.
Hiki i nā poʻe maʻi antagonist Vitamin K ke hoʻohana i ka waiwai INR e ana i ko lākou koko coagulation. ʻOiai ʻo ka poʻe olakino he INR waiwai o 1, ʻo ke koko i nā mea maʻi e like me B. i loaʻa i ka fibrillation atrial a pono e pale i ka thrombosis, ua hoʻonohonoho ʻia i kahi waiwai INR o 2 a 3. Me lākou, ʻo ka pahuhopu e loaʻa nui " ʻoi aku ka lahilahi o ke koko ma mua o ka mea maʻamau.
Ma ka haʻawina i haʻi ʻia mai ka makahiki 2007, ua hāʻawi ʻia nā mea maʻi me nā koina INR fluctuating i 150 µg o ka vitamina K a i ʻole kahi hoʻomākaukau placebo i kēlā me kēia lā no ʻeono mahina. I ka hui vitamina K, ua hoʻokūpaʻa ʻia nā waiwai INR i 33 o 35 mau mea maʻi, ʻaʻole i loaʻa i ka hui placebo. Ua hōʻoia ka loiloi 2013 i kēia mau ʻike ma o ka nānā ʻana o ʻelima mau haʻawina
Eia kekahi, i ka hoʻomaka ʻana o 2003, ua hōʻike ʻia kahi noiʻi ʻana i nā ʻiole i hiki i ka lawelawe ʻana o ka huaora K2 ke pale aku i nā holoholona i mālama ʻia me warfarin e kūʻē i ka arteriosclerosis. Eia naʻe, ʻaʻohe hopena o ka huaora K1 ma ʻaneʻi, no laila, ʻoi aku ka maikaʻi o ka lawe ʻana i ka huaora K2.
Pono ʻoe e lawe i ka vitamina K2 inā pono ʻoe e lawe i nā mea hoʻokahe koko?
ʻOiaʻiʻo, ʻaʻole pono ʻoe e lawe koke i ka huaora K2 me kāu mau mea hoʻokahe koko. Pono ʻoe e hana i kēia ma ke kūkākūkā ʻana me kāu kauka ke hoʻomaʻamaʻa ʻo ia iā ia iho me ke kūlana haʻawina i hōʻike ʻia ma aneʻi.
Ua lawa pinepine - e like me ka mea i kuhikuhi ʻia ma luna - e lawe i ka nui like o ka huaora K i kēlā me kēia lā me kāu ʻai. He mea nui ka loaʻa ʻole o nā loli nui ma ʻaneʻi. No laila, mai ʻai ʻoe i ʻelua ʻāpana ʻōpae i kēia lā, ʻelua ʻai kale i ka lā ʻapōpō, a laila ʻaʻole loaʻa i nā mea kanu no nā pule ʻelua. Akā, e hōʻoia e loaʻa iā ʻoe kahi lako mau o ka huaora K mai nā mea kanu olakino i waiwai i ka huaora K.
Inā makemake ʻoe e lawe i ka huaora K, e koho i ka huaora K2 - ʻo ia hoʻi ke ʻano mea kanu MK-7, no ka mea, ʻoi aku ka maʻalahi o kēia i ke kino e ʻeli ai ma mua o ka holoholona MK-4.
Ke kōkua nei nā mea antagonist vitamin K?
Me nā hopena ʻaoʻao a pau o nā antagonists vitamin K i helu ʻia ma luna, ʻōlelo maoli ka mea i hoʻopilikia ʻia iā ia iho ʻaʻole pili kēia i nā mea āpau a makemake kekahi e ʻae i kekahi a i ʻole nā hopena ʻaoʻao ʻē aʻe inā palekana kekahi i ka wā e hiki mai ana mai nā hanana weliweli. e like me ka thrombosis. embolism, stroke, a me ka puʻuwai.
Akā ʻaʻole maopopo kēlā. Ua hōʻike ʻia kahi noiʻi kahiko mai ka makahiki 1994 i nā poʻe maʻi (65 mau makahiki a ʻoi aʻe) me ka fibrillation atrial, pono e mālama ʻia nā kānaka 33 me nā antagonists vitamin K e pale i ka hahau ʻana i hoʻokahi wale nō o kēia mau mea maʻi. No laila, ʻo 1 ka nui o ka pā i 33. I nā poʻe maʻi ʻōpio (ma lalo o 65) ʻaʻole hiki ke hoʻoholo i ka hopena kōkua.
Ua hōʻike ʻia kahi loiloi hou mai ka makahiki 2017 ʻaʻole ʻoi aku ka maikaʻi o nā mea hoʻokahe koko ma mua o kahi placebo i ka pale ʻana i ka make mai ka thrombosis vein hohonu (a i ʻole pulmonary embolism).
Eia nō naʻe, he nui nā haʻawina i hōʻike i ka hopena pale o nā mea hoʻokaʻawale koko, no laila ʻaʻole pono e wehewehe ʻia ke kālā he mea ʻole. Eia naʻe, ʻaʻole ia e ʻeha ke noʻonoʻo e pili ana i nā hana ʻē aʻe a i ʻole nā mea ʻē aʻe.
Aia nā mea ʻē aʻe i nā mea hoʻokahe koko?
I ka wā e pili ana i nā mea ʻokoʻa i nā mea hoʻokahe koko, nui ka poʻe e ʻimi nei i nā ala ʻē aʻe. Ua ʻōlelo ʻia he mau lāʻau lapaʻau maoli e hoʻoheheʻe i ke koko e like me nā lāʻau lapaʻau akā ʻaʻohe hopena ʻaoʻao. ʻOiai aia nā lāʻau lapaʻau maoli e loaʻa ai ka hopena maikaʻi i ke koko koko, ʻaʻohe mea i ʻike inā lawa maoli ka lawe ʻana i kēia mau hoʻomākaukau e pale aku i ka thrombosis, ka hahau ʻana, a me ka puʻuwai puʻuwai.
Mai ka manaʻo holoʻokoʻa, akā naʻe, ʻaʻole ia e pili ana i ka hoʻololi wale ʻana i kahi lāʻau lapaʻau no kekahi, akā e pili ana i ka hoʻololi ʻana i ke ʻano holoʻokoʻa o ke ola i ke ala e hiki ai i ke kino ke hoʻōla a hoʻōla hou iā ia iho. ʻO ka lawe wale ʻana i kahi lāʻau lapaʻau - inā he lāʻau maʻamau a kūlohelohe paha - no laila ʻaʻole loa e alakaʻi i ka ho'ōla.
He haʻawina mai 2013 mea hoihoi i loko o kēia pōʻaiapili, ka mea, aole wale i hoike mai i ka poe i hahai i na rula o ka Mediterraneanʻai meaʻai i emi pinepine mai atrial fibrillation, akā, i keia ano o ka meaʻai alakai i spontaneous hoola o ka atrial fibrillation hiki.
Ka hopena: ka huaora K a me nā mea hoʻokahe koko
ʻO kēlā me kēia mea e lawe i nā mea hoʻoheheʻe koko o ka ʻano antagonist vitamin K hiki ke ʻai i nā meaʻai momona i ka huaora K me ka pilikia ʻole akā pono e hōʻoia i ka hoʻolako mau ʻana i kēia mau meaʻai i waiwai i ka huaora K a pale i nā loli ma kēia ʻano, ʻo ia hoʻi e nānā mau i ka INR i ka manawa like . helu helu.
Inā makemake ʻoe e lawe i ka huaora K hou, hiki iā ʻoe ke hana pēlā, akā pono ʻoe e kūkākūkā i kēia ana me kāu kauka. Hiki i ka lawe ʻana i ka Vitamin K ke alakaʻi i ka hoʻopaʻa ʻana o nā koina INR i hoʻololi mua ʻia.
ʻO ka lawe ʻana i ka huaʻa K2 e like me MK-7 e koi i nā kau haʻahaʻa ma mua o MK-4. No ka mea hiki ke hoʻopili maikaʻi ʻia ka MK-7 e ke kino ma mua o MK-4.
ʻO ka ASA a me ka vitamina K
He ʻano hana ʻokoʻa ka hana ʻana o nā antagonists Vitamin K (Marcumar, a me Warfarin) ma mua o ka ASA i ka wā e pili ana i ka ʻemi koko. ʻOiai e hoʻohaʻahaʻa ana nā antagonists i ka vitamina K, ʻaʻole ʻo ASA. No laila, ʻaʻohe mea e like me ka hemahema o ka huaora K pili i ka ASS.
Inā, ma ke ʻano he maʻi ASD, pono ʻoe i ka vitamina K, no ka laʻana, no kou lawe ʻana i ka huaora D a i ʻole no ka haʻahaʻa o kāu ʻai i ka vitamina K a i ʻole - ma ke kūkākūkā ʻana me ke kauka - e pale i ka arteriosclerosis, a laila hiki iā ʻoe ke lawe i ka vitamina K2 i kahi ka lawe ʻana i kēlā me kēia maʻi kūpono, e laʻa me B. 50 – 100 µg i kēlā me kēia lā (e kūkākūkā me ke kauka a i ʻole ke kauka lapaʻau ʻole). Me nā hāʻule o ka huaora K2 (ma kahi o nā capsules) hiki iā ʻoe ke hoʻoinu i ka lāʻau lapaʻau i kēlā me kēia.
