Allison Turner
Ngokophononongo lwakutshanje, ivithamin D inokuxhasa ngokufanelekileyo unyango lwe-multiple sclerosis (MS). Apha ungafumanisa ukuba yeyiphi idosi efunekayo.
Idosi ye-vitamin D ephantsi yonyusa umngcipheko we-MS
Izifundo ezininzi zibonise unxibelelwano phakathi kokutya okuphantsi kwevithamin D kunye nomngcipheko owongeziweyo we-MS. Kukwayaziwa ukuba inqanaba eliphantsi levithamini D kwizigulana ze-MS zonyusa iimpawu. Abaphandi ngoku baye baphanda ukuba i-cholecalciferol, esihlala siyibiza ngokuba yi-vitamin D, ingaba luncedo kangakanani kubantu abane-multiple sclerosis.
Kuphononongo lwabo, izazinzulu kwiYunivesithi yaseJohns Hopkins eBaltimore zahlalutya unikezelo lwevithamini D yabantu abadala abangama-40 abaneminyaka eyi-18 ukuya kwengama-55 abane-MS ebuyela umva. Ngolu hlobo lwesifo, iimpawu zinokusombulula ngokupheleleyo, kodwa zingabangela umonakalo ongunaphakade.
Njengenxalenye yophononongo, izigulane ze-40 zifumene idosi ephezulu kakhulu yemihla ngemihla ye-vitamin D3 (iiyunithi ze-10,400 zamazwe ngamazwe - ezilingana ne-0.26 milligrams) okanye i-dose ephantsi kakhulu (800 IU - okt 0. 02 milligrams). Oko kungaphezulu nje kancinci kunomthamo ocetyiswayo wemihla ngemihla (600 IU okanye 0.015 milligrams).
Uvavanyo lwegazi lwalusetyenziselwa ukulinganisa amanqanaba e-vitamin D yomthathi-nxaxheba ngamnye kunye neempendulo ze-T cell ezinxulumene ne-MS emva kweenyanga ezintathu nezintandathu. Kwi-multiple sclerosis, iiseli zomzimba ezibizwa ngokuba ziiseli ze-T zihlasela i-myelin sheath. Lo maleko okhuselayo, owaziwa ngokuba yi-myelin sheath, ukhusela i-nerve fiber kwaye ngaloo ndlela uvuselela ukuhanjiswa ngokukhawuleza kwemiqondiso yombane. Ukuba ii-T-cell zichaphazelekayo, ukuhanjiswa kwe-stimuli kuphazamiseka. Isiphumo: iiseli zemithambo-luvo ziyafa kwaye abo bachaphazelekayo kufuneka balwe nobunzima bokulungelelanisa kunye neempawu zokukhubazeka.
I-Vitamin D iyacotha ukuqhubeka kwe-MS
I-vitamin D ikuthintela njani ukuqhubeka kwesifo se-MS? Isazinzulu uGqr. UPeter A. Calabresi kunye neqela lakhe bafika kwisigqibo esilandelayo: Ukuthatha umthamo ophezulu we-vitamin D3 unqanda iiseli ze-immune ezingalunganga ekuhlaseleni inkqubo ye-nervous. Esi seso sizathu sokuba inani lee-T-cells ezingahambi kakuhle lehla kuphela kwigazi lezo zigulana zifumene idosi ephezulu yevithamini. Kuzo zonke i-0.005 milligram yokwanda kwe-vitamin, i-T-cell count yehla ngepesenti enye.
Ingakanani iVithamin D ekufuneka izigulana zeMS zitye?
Iingcali zincoma ixabiso lemihla ngemihla le-0.05 milligrams ye-vitamin D3 kwizigulane ze-MS - ngokubonisana nodokotela obaphathayo.
