I-Galactose: Impembelelo kunye nokutya okuchanekileyo kwe-Mucus Sugar

I-Galactose yiswekile elula - njengeglucose okanye i-fructose. Nangona kunjalo, yiswekile ekhethekileyo kakhulu. IGalactose icetyiswa kakhulu kubantu abanesifo seswekile – nakubantu abane-Alzheimer's. Igalactose ilungele iimbaleki kwaye ide ikhusele amazinyo ekuboleni kwamazinyo. Oko kuvakala njengeswekile egqibeleleyo. Ngaba ngokwenene igalactose igqibelele ngolo hlobo? Okanye ngaba kukho nezinto ezingeloncedo?

Yintoni igalactose, D-galactose, kunye neswekile ye-mucus?

I-Galactose yi-carbohydrate, ebizwa ngokuba yishukela elula (i-monosaccharide) - njenge-glucose (dextrose) okanye i-fructose (ishukela yeziqhamo). NgesiJamani, igalactose ikwabizwa ngokuba yi-slime iswekile kuba igalactose ifumaneka kulwelwesi lwamafinyila, phakathi kwezinye izinto.

Igalactose inokuphinda ibhalwe ngo “k”, okt igalactose. Upelo luka "k" luvela kwigama lesiGrike elithi gálaktos. Kwi-jargon yobugcisa, i-spelling galactose isetyenziswa.

I-D-galactose nayo ihlala ifundwa. Unokufunda ukuba kuthetha ukuthini oko kwicandelo elilandelayo. Nangona kunjalo, ukuba kuthiwa i-galactose kuphela okanye ibhaliwe, ihlala ithetha i-D-galactose.

Ziziphi izinto ezisetyenziselwa i-galactose?

IGalactose ineendlela ezintathu eziphambili zokusetyenziswa:

• Umthombo wamandla wengqondo kwaye ke kuthintelo oluxhasayo kunye nonyango lwe-Alzheimer's, dementia, kunye nokudakumba.
• Umthombo wamandla kwiimbaleki, abanesifo seswekile, kunye nabantu abafumana intsebenzo ephantsi ngoku (intsimbi ye-11 okanye ezantsi kwemini).
• I-insulin-ezimeleyo kunye ne-sweetener eneswekile yegazi (nangona inamandla abuthathaka)

Isebenza njani igalactose?

Igalactose inika iiseli (nasengqondweni) ngamandla, kodwa kuphela xa isetyenziswe kwisixa esicetyiswayo. Ngoko ke, inqanaba legazi legalactose kufuneka lifikelele kugxininiso oluthile. Kuphela ke i-galactose ingena kwiiseli, apho inokuguqulwa ngokukhawuleza ibe yi-glucose kwaye ibe namandla ngoncedo lwee-enzyme ezimbini (i-galactokinase kunye ne-uridyl transferase).

I-Galactose ngoko ngumthombo okhawulezayo wamandla kwaye ngoko ke iphinda isetyenziswe njenge-pick-me-up xa ukusebenza kuphantsi okanye kwimidlalo. Ngenxa yokuba i-galactose i-metabolized ngaphandle kokuguquguquka kweswekile yegazi eyaziwayo ukuba yenzeke ngeswekile eqhelekileyo, enokuthi ikhokelele kwiminqweno kunye / okanye ukuhlaselwa kokudinwa.

Ekubeni i-galactose ayifuni i-insulin ukuze ingene kwiiseli, ingumthombo obalulekileyo wamandla, ngakumbi kwizifo ezinxulumene nokumelana ne-insulin okanye ukunqongophala kwe-insulin (umzekelo, isifo seswekile, ukudakumba, i-Parkinson, okanye i-Alzheimer's).

Ngaba igalactose iyanceda kwi-Alzheimer's?

Isifo i-Alzheimer's sisoloko sibizwa ngokuba sisifo seswekile se-3 kuba kukho ukuphazamiseka kwemetabolism ekusetyenzisweni kweswekile, oko kukuthi ukunganyangeki kwe-insulin kwiiseli zobuchopho (ngenxa ye-insulin receptors enesiphako) ukuze ingqondo ingasakwazi ukubonelelwa ngeglucose eyaneleyo kunye neswekile. amandla.

Ezinye izazinzulu zinoluvo lokuba oku kuxhathisa kwe-insulin kwiiseli zobuchopho ngomnye woonobangela besifo sengqondo esiyingozi. Iiseli azikwazi ukuvelisa amandla aneleyo kwaye ngenxa yoko azisayi kulahla inkunkuma yazo ye-metabolic. Kungoku kuphela apho iidipozithi ezoyikekayo (i-plaque) zenza kwaye ngoku kuphela iiseli zemithambo-luvo ziqala ukufa.

Omnye wezi nzululwazi yayinguWerner Reutter, owayekhe wangugqirha kunye nengcali yamachiza eFreie Universität Berlin, owafunda igalactose kunye nefuthe layo kwisifo sengqondo esixhalabisayo ukususela ekupheleni kweminyaka yee-1970 de kwakufutshane phambi kokuba asweleke ngoMeyi ka-2016.

Ingqondo idinga amandla amaninzi - phantse isiqingatha se-carbohydrates efakwe imihla ngemihla (okanye i-glucose evela kubo) iyadingeka ukondla iiseli ezingqondweni ukuvavanya ukuvakalelwa, ukucinga, ukwenza izigqibo, njl.

Igalactose ngumthombo wamandla wengqondo

Kodwa ukuba i-glucose ayinakuphinda isetyenziswe ngenxa yokunganyangeki kwe-insulin okanye i-insulin receptors engasebenzi, kuthekani ke? Umntu ngoku unokubonelela ngemizimba ye-ketone yengqondo, eveliswa sisibindi kumanqatha ngexesha lokutya kwe-ketogenic. Nangona kunjalo, ukutya kwe-ketogenic akusebenzi kubantu abaninzi. Igalactose inokuba yenye into enokwenzeka.

Oku kungenxa yokuba igalactose inokuqukuqela kwiiseli ngaphandle kwe-insulin. Ke igalactose ayikhathali (njengemizimba yeketone) nokuba i-insulin receptors ziyasebenza okanye hayi.

I-Galactose ikhusela iimpawu ze-dementia - kwiigundane

U-Reutter kunye nosokhemesti uMelitta Salkovic-Petrisic ovela kwiYunivesithi yaseZagreb wasebenzisa iimpuku ezinohlobo lwe-1 yeswekile, esele ibonise ukuphazamiseka kwengqondo okufana ne-Alzheimer ngenxa yokunqongophala kwe-insulin kwaye ke ngoko isetyenziswa ngokuphindaphindiweyo njengemizekelo yovavanyo lophando kwi-Alzheimer's disease, ukufumanisa. indlela esebenza ngayo rhoqo imihla ngemihla yolawulo lomlomo lwe-200 mg galactose ngekhilogram yobunzima bomzimba obuchaphazele ezi ngxaki.

Ukunika igalactose inyanga kanye emva kokuba iiseli ezivelisa i-insulin kudakada zifile kuthintela ukuphazamiseka kwengqondo (umz. inkumbulo engalunganga) ebeza kubangwa kukunqongophala kwe-insulin.

Uphando olongezelelweyo lubonise ukuba iidosi phakathi kwe-100 kunye ne-300 mg ngekhilogram yobunzima bomzimba yayisebenza ngokulinganayo. Engqondweni, nangona kunjalo, i-galactose concentration emva kokulawulwa komlomo ayizange inyuke kakhulu njengedosi efanayo xa ilawulwa ngumzali, okt itofwe. Emva kokulawulwa kwabazali, ukugxilwa kwengqondo kwakuphindwe kaninzi kunokuba emva kokulawulwa komlomo kwidosi efanayo. Yiyo loo nto iinaliti zegalactose ziyonakalisa ingqondo, ngelixa ukungeniswa ngomlomo kunokunceda ingqondo.

Isebenza njani igalactose kwiimbaleki?

Xa uqeqesha ngamandla, i-lactic acid kunye ne-ammonia zakha kwizihlunu zakho. I-ammonia, yona, ivimba i-insulin receptors ukuze iswekile ingakwazi ukufunxwa lula, nto leyo ethoba ukusebenza. Ukuba ngoku uthatha i-galactose, iiseli zinokubonelelwa nge-glucose nangona i-insulin receptors evaliweyo, ephucula ukusebenza kwakhona.

Kwi-Alzheimer's, kwakhona, kukho inqanaba elongezelelweyo le-ammonia, elinokuthi lichaze ukuxhathisa kwe-insulin ngolu hlobo lwe-dementia.

Isebenza njani igalactose kwi-sepsis?

I-insulin receptors ayinakukwazi ngoku ngasentla kuphela. I-ammonia ivaliwe, kodwa kunye nezinye izinto, ezifana ne-cytokines (izithunywa ezivuthayo), eziveliswa ngokugqithisileyo ngexesha le-sepsis. Kuphononongo lokulinga lwaseJamani kunye nezigulana ezingama-70 ze-sepsis, ukulawulwa kwegalactose kuthiwa kungqineke kuluncedo kakhulu kwaye kuxhase ukubuyiswa kwezigulana kakuhle kakhulu.

I-Sepsis ikwabizwa ngokuba "yityhefu yegazi". Kukusabela okugqithisileyo kwenkqubo yokuzikhusela yomzimba kumxholo wosulelo, apho iinkqubo eziqinileyo zokudumba (isiqhwithi secytokine) kunye nokuphazamiseka kokusebenza kwemithambo yegazi kwenzeka ukuze kuliwe ne-pathogen. Kwiimeko ezimbi kakhulu, i-edema ye-pulmonary inokukhula kwaye ekugqibeleni ingaphumeleli kwizitho ezininzi.

Ngaba igalactose iyawachaphazela amanqanaba eelipids zegazi?

Amanqanaba aphezulu e-fat fat (i-triglycerides) ngumngcipheko obalulekileyo wezifo ze-cardiovascular, ezifana nesifo senhliziyo (i-calcification yemithambo yegazi enikezela intliziyo). Inqanaba le-lipid yegazi emva kokutya libonisa umngcipheko we-cardiovascular better than fast blood lipid level. Amaxabiso angaphezulu kwe-3.5 mmol / l (iyure ezi-1 ukuya kwezi-8 emva kokutya) kathathu umngcipheko wokufa ngenxa yesifo senhliziyo xa kuthelekiswa namaxabiso angaphantsi kwe-1 mmol / l.

Amanqanaba e-lipid egazi awachaphazeli kuphela uhlobo kunye nesixa samafutha asetyenzisiweyo, kodwa kunye nohlobo kunye nobungakanani be-carbohydrates esetyenzisiweyo. Ngokomzekelo, i-Fructose inyusa izinga lamafutha egazi (ngaphezu kwe-glucose) kuba ivuselela ukubunjwa kwamafutha amatsha kwi-carbohydrates esibindini kwaye kwangaxeshanye iyancipha ukutshisa kwamafutha.

I-Galactose (xa idliwe ngamafutha) inefuthe elifanayo kumanqanaba e-lipid yegazi njenge-fructose, nangona ingekho kakhulu, kodwa ibaluleke kakhulu kune-glucose. Nangona kunjalo, inani elikhulu leswekile lisetyenziswe kwisifundo esichaphazelekayo - kwimeko ye-galactose, yayingu-58 g ngesidlo.

Ngaba igalactose iyawonakalisa amazinyo?

Igalactose yiswekile, kodwa ayinabungozi emazinyweni. Okuphikisanayo. Ngokutsho kwesifundo se-2020, i-galactose inqanda ukubunjwa kwe-biofilm ye-caries-causing bacteria (i-Streptococcus mutans), ngelixa iswekile ikhuthaza ukuphuhliswa kweebhaktheriya ezingenabungozi kwi-flora yomlomo. Umphumo we-anti-caries wawusele ubonwe kwiindawo eziphantsi ze-galactose, ngoko kuhle kakhulu ukuba kucatshangelwa ukusebenzisa i-galactose kwiimveliso zokunakekelwa kwamazinyo kwixesha elizayo.

Kwangowe-1989, uphando lwabonisa i-caries-inhibiting effect yegalactose. Isisombululo se-5% se-galactose sinciphisa i-caries kakuhle, inqanda i-caries biofilm, kwaye inciphisa ukukrazula kwendawo yokuhlafuna yamazinyo - okokugqibela mhlawumbi ngenxa yokunyuka kwenqanaba le-calcium kwi-serum, ebizwa ngokuba yi-galactose.

Nokuba isisombululo se-galactose se-0.5 ekhulwini sisenako ukunciphisa i-biofilm, kodwa ayisekho caries. I-Galactose inepropati yokuzibandakanya kwi-receptors yento ebizwa ngokuba yi-tooth surface (pellicle) kwaye ngaloo ndlela ikhusela iibhaktheriya ezinobungozi, umzekelo, iibhaktheriya ze-B. Caries.

I-cuticle yezinyo yifilimu encinci eyenza kwakhona ngokukhawuleza emva kokuxubha amazinyo (ukusuka kwiiprotheni ezisuka kwi-saliva, phakathi kwezinye izinto) kwaye igubungele ubuso bezinyo ukuyikhusela. I-pellicle ikhusela kwi-abrasion kunye ne-asidi, kodwa ingabonelela ngendawo yokuzalela iibhaktheriya ezinobungozi kwaye ngoko kaninzi yenza isiseko se-plaque yamazinyo.

Nangona kunjalo, ukuba i-galactose ithintela iibhaktheriya ezinobungozi ukuba zinamathele ngokwazo, ukwakheka kwe-plaque kuyathintelwa.

Ngaba i-galactose vegan?

Igalactose yendalo kwiziqhamo, imifuno, kunye nemifuno yi vegan. Nangona kunjalo, igalactose ethengiswa njengesongezelelo sokutya ayidli ngokuba yi-vegan njengoko ivela kwi-whey, imveliso yezilwanyana.

Iinkcazo zeemveliso zezinye iimveliso zegalactose zichaza ngokungalunganga "i-vegan", ethi, xa ijongwa ngokusondeleyo, ibonakale ingalunganga kwaye umenzi uthetha "imifuno". Xa ebuzwa kabini (!), Omnye umenzi (i-Vita world) wathi imveliso yayo yi-vegan. Nangona i-lactose isetyenziselwa ukuvelisa i-Vita world galactose, ekubeni imveliso yokugqibela (ngenxa yokuguqulwa kwe-enzymatic) ayisekho i-lactose, imveliso ngoku i-vegan. Nkqu nolwazi lokuba iimveliso ze-vegan zingenakwenziwa kwimveliso yemvelaphi yezilwanyana kwaye i-lactose-free ayithethi ukuba i-vegan ayizange itshintshe imbono yomenzi.

Asikafumani umgubo wegalactose oyivegan okwangoku. Ukuba ufumana enye, nceda uqhagamshelane nathi usebenzisa ifomu yethu yoqhagamshelwano. Enkosi!

IVegan galactose kufuneka ivele kwiimbotyi, umz. B. Iichickertyisi zinokuveliswa, kuko konke ukutya kwezityalo okuseneyona galactose kakhulu. Nangona kunjalo, umxholo wegalaktosi apha nawo uphantsi kakhulu xa uthelekiswa nowo whey, ukuze isivuno sibe sincinci ngokuhambelanayo kwaye iziphumo zegalactose ziya kuba zibiza kakhulu kunokuba sele zinjalo.

Ukuba u-vegan, nikela ingqalelo ngokusondeleyo kwi-galactose kuphela kodwa nakwezinye izongezo zokutya kunye neengxelo ezenziwe ngumenzi kwaye ungabuzi nje ukuba imveliso yi-vegan, kodwa kunye nokuba yenziwe ngantoni.

Kutheni kunganelanga nje ukusela ubisi oluninzi?

Iimveliso zobisi aziqukethe i-galactose yamahhala, i-lactose kuphela. Abanye abantu abadala banokunganyangeki kwe-lactose, oku kuthetha ukuba abanako ukuphula i-lactose ibe yi-glucose kunye ne-galactose. Nangona enye inxalenye ine-enzyme ehambelanayo (i-lactase), i-lactase idla ngokungasebenzi ngokwaneleyo, nakubantu abadala abangenayo i-lactose engavumiyo, ukuqinisekisa umgangatho ophezulu ngokwaneleyo we-galactose yamahhala egazini.

Ngenxa yokuba igalactose ithathwa kuphela ngamaseli xa inqanaba legalactose egazini lifikelele kwinqanaba elithile. Ngoko akuyi kuba luncedo ukuthatha i-lactose ecocekileyo (iswekile yobisi) ngezixa ezikhulu.