Tracy Norris
Itiye elihlaza liwumthombo wentsha enamandla ezempilo abonakala engapheli, ikakhulukazi e-Asia. Ngenxa yokuthi isiphuzo sikazwelonke saseJapane asifanele kuphela ukuvimbela umdlavuza, ukukhipha ubuthi, nokuqinisa inhliziyo, siphinde sikhuthaze ukukhiqizwa kwamangqamuzana amasha ebuchosheni, angathuthukisa inkumbulo yakho, enze kube lula ukufunda izinto ezintsha, futhi uvimbele noma wehlise ijubane. ukuthuthukiswa kokuwohloka komqondo. Uma ungathandi itiye eliluhlaza, ungathatha futhi itiye elihlaza elikhishwe ngendlela ye-capsule.
Itiye elihlaza likhuthaza ukwakheka kwamaseli amasha ezinzwa ebuchosheni
Ingabe uyakwazi lokho? Ngemva kwenkomishi yetiye eliluhlaza, ikhanda liba sobala ngokuphelele. Ungakwazi ukugxilisa ingqondo imisebenzi engcono futhi enzima ngokwengqondo kulula kakhulu ukuyiqeda. Akumangalisi njengoba esinye sezithako eziyinhloko ezisebenzayo etiyeni eliluhlaza - i-epigallocatechin gallate, noma i-EGCG ngamafuphi - ingashukumisa ukwakheka kwamangqamuzana ezinzwa amasha ebuchosheni (neurogenesis), ucwaningo olwatholwa emuva ngo-2012.
Kuze kube yiminyaka yawo-1990, kwakukholelwa ukuthi ukwakheka kwamangqamuzana ezinzwa amasha ebuchosheni kwakungenakwenzeka kubantu abadala. Nokho, okwamanje, siyazi ukuthi amangqamuzana ezinzwa angaphinde akheke kaningi kubantu abadala - ngisho nasebudaleni. Ngakho-ke kuyikhono lempilo yonke lobuchopho. Kubuye kubizwe ngokuthi yi-neural plasticity, okusho ukuthi ubuchopho nezakhiwo zabo zingashintsha, ziguquke, futhi zivumelane nezimo njengoba kudingeka, njengalapho ufunda okuthile okusha, kungaba ngokwengqondo (isib. ulimi, umdlalo, noma ithiyori ye ilayisensi yokuhamba ngomkhumbi) noma yemvelo (isib. umdlalo omusha, ukuvivinya umzimba okusha).
Itiye elihlaza lokuvikela nokwelapha ukuwohloka komqondo
Endabeni yezifo ze-neurodeergenerative ezifana nokuwohloka komqondo noma ukwehla kokusebenza kwenkumbulo, ipulasitiki ye-neuronal futhi ngaleyo ndlela ukwakheka kwamangqamuzana ezinzwa ezintsha kuncipha. Uma i-EGCG evela ku-green tea ivuselela ukwakheka kwamangqamuzana amasha ezinzwa, khona-ke into ingasetshenziselwa ukuvimbela nokwelapha izifo ze-neurodeergenerative - lesi yisiphetho sososayensi abahlukahlukene, izifundo zabo esethula ngezansi.
I-EGCG kusuka etiyeni eliluhlaza ukuze uthole inkumbulo enhle
Ocwaningweni okukhulunywe ngalo ngenhla, uProfesa Yun Bai waseChinese Third Military Medical University eChongqing, isibonelo, wabonisa ukuthi i-EGCG evela etiyeni eliluhlaza ingakhuthaza ngempela i-neurogenesis ku-hippocampus. I-hippocampus iyingxenye yobuchopho ebhekele inkumbulo nokufunda. Kulapho ulwazi ludluliselwa khona lusuka kumemori yesikhashana luyiswe kwinkumbulo yesikhathi eside ukuze ungakhohlwa okufundile ngemva kwezinsuku ezimbalwa, futhi esikhundleni salokho ukwazi ukukukhumbula.
Amagundane athole i-EGCG etholakala etiyeni eliluhlaza afunde ngokushesha okukhulu futhi abe nenkumbulo engcono yendawo kuneqembu lokuqhathanisa elingazange lithole i-EGCG.
Itiye eliluhlaza lenza idiphozithi ye-Alzheimer ingabi nangozi
I-EGCG evela etiyeni eluhlaza ayikhuthazi nje ukwakheka kwamaseli amasha ezinzwa. Lo muthi ungenza futhi ama-protein anobuthi (ama-plaque) ajwayelekile esifo i-Alzheimer's angabi nangozi - okungenani ekuhlolweni kwaselabhorethri ngamaseli, njengoba ucwaningo lwango-2010 selubonisile.
Abacwaningi abaholwa u-Jan Bieschke we-Max Delbrück Centre for Molecular Medicine eBerlin bathole ukuthi i-Alzheimer's and Parkinson's-typical protein deposits, enobuthi kakhulu kumangqamuzana ezinzwa futhi eholela ekufeni kwawo, angenziwa angabi nangozi ngezithako ezisebenzayo etiyeni eliluhlaza. .
Uma unikeze i-EGCG kumangqamuzana athintwe amadiphozithi anobuthi futhi abe ne-metabolism ekhawulelwe, okungukuthi abe buthaka kakhulu, ngakho-ke ngenxa ye-EGCG amadiphozithi aguqulwa abe amadiphozithi angenabuthi amaseli asengakwazi ukuwadiliza kalula.
Ukukhishwa kwetiye elihlaza kwandisa ukusebenza kobuchopho
Ngo-2014, ososayensi baseBasel abasebenza noProfessor Christoph Beglinger kanye noStefan Borgwardt bashicilela imiphumela yocwaningo ethakazelisayo kumagazini i-Psychopharmacology: Bathola ukuthi ukukhishwa kwetiye eliluhlaza kungathuthukisa ukuxhumana ebuchosheni (ukuxhumana phakathi kwamangqamuzana ezinzwa) kanjalo namakhono okuqonda.
Abahlanganyeli bocwaningo kwakungamavolontiya wesilisa anikezwa isiphuzo esithambile esinokukhishwa kwetiye eliluhlaza ngaphambi kokuba bacelwe ukuthi baxazulule imisebenzi edinga inkumbulo yokusebenza ikakhulukazi. Imemori esebenzayo imunca ulwazi, ilugcine isikhathi esifushane, bese iluxhuma - uma kunesidingo - nolwazi olukhona kumemori yesikhathi eside.
Ngosizo lwe-MRI scan, abacwaningi bakwazi ukukhombisa ukuthi ubuchopho balawo madoda ayethole i-extract tea eluhlaza bubonise izinga eliphezulu kakhulu lokuxhumana phakathi kwezifunda zobuchopho ngabanye. Ngesikhathi esifanayo, amadoda etiye elihlaza akwazi ukuxazulula imisebenzi kangcono. Ngakho i-green tea extract ingasekela inkumbulo yokusebenza. Ngokuqondile lezi zakhiwo zingaba usizo ekwelapheni ukukhubazeka kwengqondo ezifweni ze-neurodegenerative ezifana nokuwohloka komqondo - ngakho umusho ophethayo esifinyezweni socwaningo.
Sebenzisa zonke izithako ezisebenzayo ezivela etiyeni eliluhlaza!
Ngo-2017, u-Beglinger nethimba labo bahlaziya izifundo ezingu-21 ngetiye eliluhlaza nengqondo, okuhlanganisa nezilingo ezi-4 ezilawulwa ngokungahleliwe kanye nezifundo eziyi-12 eziphambanayo. Ezifundweni eziphambanayo, abahlanganyeli abafanayo bathola kokubili - into esebenzayo bese, ngemva kwekhefu elifushane, ukulungiswa kwe-placebo.
Ukuhlaziywa kwathola ukuthi itiye eliluhlaza linciphisa izimpawu zengqondo, njenge-B. linganciphisa ukukhathazeka, namakhono okuqonda, anjalo. B. inkumbulo noma ikhono lokugxilisa ingqondo lithuthukisiwe kanye nokusebenza kobuchopho, okunjalo. B. ingenza imemori isebenze noma imemori esebenzayo. Abacwaningi bagcizelele ukuthi le miphumela yetiye eluhlaza ayikwazi ukubhekwa njengesithako esithile esisebenzayo, kodwa iwumphumela wezinto eziningana ezivela etiyeni elihlaza ezihlangene zibe nomphumela omuhle.
Ngakho-ke ngeke kunconywe ukuthatha i-EGCG emsulwa noma amaphilisi e-L-Theanine amsulwa. Kunengqondo ukuphuza itiye eliluhlaza eliphilayo noma ukuthatha amaphilisi akhipha itiye elihlaza aphezulu.
Okunye ukuhlaziya okuvela ku-2018 kuphinde kwafinyelela esiphethweni sokuthi itiye eliluhlaza noma i-green tea powder ingasekela futhi ithuthukise imisebenzi yengqondo kahle kakhulu uma iqhathaniswa neqembu le-placebo elifanele.
Uma itiye eliluhlaza lithe xaxa, kunciphisa ingozi ye-Alzheimer's
Ukubuyekezwa kuka-2019 kuphinde kwabonisa ukuthi izifundo eziningi ezitholakalayo zithole ukuhlobana okuhle phakathi kokusetshenziswa kwetiye eliluhlaza kanye nokuvela kwezifo ze-neurodeergenerative, okungukuthi i-Alzheimer's kanye nezifo ezifanayo mancane amathuba okuba kuphuzwe itiye eliluhlaza kakhulu.
Ngakho-ke, uma ufuna ukwenzela ubuchopho bakho okuthile okuhle, uma ufuna ukuvimbela izifo ze-neurodeergenerative, noma noma ngabe usuvele uqaphela ukuphela kwenkumbulo yokuqala, ungahlanganisa itiye eliluhlaza ohlelweni lwakho lokuvimbela noma lokwelapha.
